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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPRM All Species: 10.91
Human Site: T829 Identified Species: 26.67
UniProt: P28827 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28827 NP_001098714.1 1452 163682 T829 P S S F T M K T N T L S T S V
Chimpanzee Pan troglodytes XP_512029 1532 172097 T900 P S S F T M K T N T L S T S V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537326 1352 152839 N762 S Y A E Q G T N C D E A F S F
Cat Felis silvestris
Mouse Mus musculus P28828 1452 163576 T829 P S S F T M K T N T L S T S V
Rat Rattus norvegicus Q64604 1898 211475 S1234 R Y A S S P Y S D E I V V Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512422 1366 153344 A776 K T T T K L S A A H N E E V L
Chicken Gallus gallus Q6YI48 1434 161661 G812 L Q E D E R L G L S F M D T H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B3DK56 1444 162642 L816 S F T D Q S T L Q E D E R M A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16621 2029 229038 R1371 E P E V S V N R N K D E P E I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9BMN8 2200 246601 H1437 F T N Y P L E H N L H Y R L M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 N.A. 85.5 N.A. 97.4 27.1 N.A. 62.1 54.4 N.A. 52.4 N.A. 25.5 N.A. 24.6 N.A.
Protein Similarity: 100 94.2 N.A. 87.5 N.A. 98.6 41.9 N.A. 75.7 72.3 N.A. 69.3 N.A. 40.4 N.A. 38.7 N.A.
P-Site Identity: 100 100 N.A. 6.6 N.A. 100 6.6 N.A. 0 0 N.A. 0 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 N.A. 20 N.A. 100 40 N.A. 26.6 13.3 N.A. 6.6 N.A. 26.6 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 0 0 0 10 10 0 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 20 0 0 0 0 10 10 20 0 10 0 0 % D
% Glu: 10 0 20 10 10 0 10 0 0 20 10 30 10 10 0 % E
% Phe: 10 10 0 30 0 0 0 0 0 0 10 0 10 0 10 % F
% Gly: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 10 10 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % I
% Lys: 10 0 0 0 10 0 30 0 0 10 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 20 10 10 10 10 30 0 0 10 10 % L
% Met: 0 0 0 0 0 30 0 0 0 0 0 10 0 10 10 % M
% Asn: 0 0 10 0 0 0 10 10 50 0 10 0 0 0 0 % N
% Pro: 30 10 0 0 10 10 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 10 0 0 20 0 0 0 10 0 0 0 0 10 0 % Q
% Arg: 10 0 0 0 0 10 0 10 0 0 0 0 20 0 0 % R
% Ser: 20 30 30 10 20 10 10 10 0 10 0 30 0 40 0 % S
% Thr: 0 20 20 10 30 0 20 30 0 30 0 0 30 10 0 % T
% Val: 0 0 0 10 0 10 0 0 0 0 0 10 10 10 40 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 20 0 10 0 0 10 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _